The use of antibiotic-loaded bone cement reduces the rate of infection by 50 % for primary total hip arthroplasty (THA) [27a]
Changing the prophylaxis protocol in primary hip and knee arthroplasty from the use of a bone cement without antibiotics to the use of PALACOS R+G led in one study to a reduction of the infection rate of 72 % for hip implants and 60 % for knee implants. [28]
Antibiotic-loaded bone cement significantly reduces the 3 year risk of revision (2.4 % for cemented with antibiotics vs. 3.3 % for cemented without antibiotics) regardless of the sliding surface [26]
