Formula: [Pt(NH3)2Cl2]
Monographs: USP, Ph. Eur., JP *
Drug Master File: available on request
* Monographs are available on request
Cisplatin
Chemical Properties
Appearance:
- Form: Powder
- Color: Yellow
Odor: Odorless
pH-value at 20 °C (68 °F): 5-7
Change in condition
- Boiling point/Boiling range: Undetermined.
Flash point: Not applicable.
Flammability (solid, gaseous): Undetermined.
Ignition temperature:
- Decomposition temperature: >285 °C (>545 °F)
Danger of explosion: Product does not present an explosion hazard.
Vapor pressure: Not applicable.
Density at 20 °C (68 °F): 3.7 g/cm³ (30.877 lbs/gal)
Bulk density at 20 °C (68 °F): 850 kg/m³
Solubility in / Miscibility with water at 20 °C (68 °F): 2.5 g/l
Handling Information
- Wear protective equipment. Keep unprotected persons away.
- Work only in fume cabinet.
- Prevent formation of dust.
- Store under lock and key and with access restricted to technical experts or their assistants only.
- Ensure good ventilation/exhaustion at the workplace.
- Open and handle receptacle with care.
Storage Information
Requirements to be met by storerooms and receptacles:
- Corrosive action on metals.
- Store in dry conditions.
- Store in a cool location.
Information about storage in one common storage facility:
- Store away from flammable substances.
- Store away from foodstuffs.
Further information about storage conditions:
- Protect from exposure to the light.
- Keep receptacle tightly sealed.
Risk & Safety Information
Classification of the substance or mixture
- Acute Tox. 2 H300 Fatal if swallowed.
- Acute Tox. 3 H331 Toxic if inhaled.
- Resp. Sens. 1 H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- Muta. 1B H340 May cause genetic defects.
- Carc. 1B H350 May cause cancer.
- Met. Corr.1 H290 May be corrosive to metals.
- Eye Irrit. 2A H319 Causes serious eye irritation.
- Skin Sens. 1 H317 May cause an allergic skin reaction.
- STOT SE 3 H335 May cause respiratory irritation.
Classification according to Directive 67/548/EEC or Directive 1999/45/EC
- Toxic
- May cause cancer. May cause heritable genetic damage. Toxic by inhalation and if swallowed.
- Irritant
- Irritating to eyes and respiratory system. May cause sensitisation by inhalation and skin contact.
