PALACOS® fast R+G*: Designed for Quick Hands

The Fastest Element of Success in Joint Replacement.

PALACOS® fast R+G* is our fastest setting bone cement, developed without a waiting phase for an average overall time of less than 6 minutes.1

PALACOS® fast R+G* is only available with added gentamicin for antibiotic prophylaxis and has been shown to provide substantially higher elution rates than other bone cements despite containing less gentamicin.1

* In the United States, PALACOS® fast R+G is indicated for use in the second stage of a two stage revision for the total joint arthroplasty after the initial infection has been cleared.

Time is Money - Spend Less with PALACOS® fast R+G*

In 1987, over 20 antibiotics were tested within PALACOS® R for their in vitro elution rates. Of the antibiotics tested, gentamicin alone demonstrated superior elution kinetics. In fact, it was shown that PALACOS® R eluted nearly 1000 µg more gentamicin over 10 days than tobramycin, and 2000 µg more than vancomycin.2

As a broad-spectrum antibiotic, gentamicin is also effective against 70% of the bacteria that cause periprosthetic joint infections.3 In addition to superior elution rates and a broad spectrum of efficacy, gentamicin’s ability to withstand the heat of polymerization4 makes it the ideal candidate for bone cements.

This makes gentamicin the antibiotic of choice for all PALACOS® antibiotic loaded bone cements (PALACOS® fast R+G*, PALACOS® R+G*, PALACOS® MV+G*, PALACOS® LV+G*).

* In the United States, PALACOS® fast R+G, PALACOS® R+G, PALACOS® MV+G and PALACOS® LV+G are indicated for use in the second stage of a two stage revision for the total joint arthroplasty after the initial infection has been cleared.

PALACOS® fast R+G* has up to 37 percent faster working times than traditional bone cements** and includes the benefits of no waiting and a very short setting time. The average overall time for PALACOS® fast R+G* is less than 6 minutes.1 

Reduction in time spent waiting on cement preparation and/or setting by using PALACOS® fast R+G* can reduce direct OR costs by as much as 50 dollars per surgery and have an opportunity cost savings of 155 dollars per surgery.5 

How much is your bone cement choice costing you?

**at 23°C operating room temperature

* In the United States, PALACOS® fast R+G is indicated for use in the second stage of a two stage revision for the total joint arthroplasty after the initial infection has been cleared.

PALACOS® fast R+G is indicated for use in the second stage of a two-stage revision for total joint arthroplasty after the initial infection has been cleared. PALACOS® fast R+G is not suitable for anchoring the femoral component of hip joint endoprosthesis.

Due to the lack of a waiting phase, vacuum cement mixing is also not recommended for use with PALACOS® fast R+G.

1 IFU PALACOS® fast R+G, 2013.

2 Wahlig H. Kinetics of the liberation of antibiotics from bone cements--results of comparative studies in vitro and in vivo]. Aktuelle Probl Chir Orthop. 1987;31:221-226.

3 Zimmerli W. Bone and Joint Infections. 2015; 132.

4 Kuehn, KD. PMMA Cements. Springer, 2014. p 131-132.

5 Childers, CP., Maggard-Gibbons, M. Understanding costs of care in the operating room. JAMA surg 2018; 153(4):e176233.