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Fractured Neck of Femur

Hip fracture is one of the most serious health care problems affecting older people. Most of the hip fractures are caused by osteoporosis and occur after a fall.1,2

Fractured Neck Of FemuriStock.com/David Marchal

Proximal femur fractures generally require hospitalisation and surgical treatment. They often lead to disability and are associated with high morbidity and mortality.3

Early surgery and coordinated care are important to help patients with fractured neck of femur (FNOF) recover faster and regain mobility.4

Hemiarthroplasty (HA) after FNOF is considered an option for less fit and less mobile patients with limited life expectancy. Advantages of HA include a short operation time and quick mobilisation of the patient associated with acceptable clinical, functional, and radiological results.5

Deep SSI Reduction from 3.5% to 1.1% in Hip Hemiarthroplasty after FNOF Using COPAL® G+C Bone Cement6

The study by Sprowson et al. (2016) concluded that the use of high dose dual antibiotic-loaded bone cement (COPAL® G+C) leads to a significant reduction in the rate of deep surgical site infection in the treatment of patients with an intracapsular FNOF, with no associated increase in other complications.

This double blinded, two arm, quasi-randomised controlled trial (RCT) was performed between 05/2008 and 11/2011 in Wansbeck General Hospital and North Tyneside General Hospital, Northumbria, UK.

Study design: quasi randomised controlled trial incl. 848 patient with fractured neck of femur suitable for cemented hemiarthroplasty treatment with a high risk for periprosthetic infection. Control group: n = 448 using low-dose single antibiotic-loaded bone cement; intervention group: n = 400 using high-dose dual antibiotic-loaded bone cement
Study design: quasi randomised controlled trial incl. 848 patient with fractured neck of femur suitable for cemented hemiarthroplasty treatment with a high risk for periprosthetic infection. Control group: n = 448 using low-dose single antibiotic-loaded bone cement; intervention group: n = 400 using high-dose dual antibiotic-loaded bone cement
Study results: Deep SSI reduction from 3.5% to 1.1% in hip hemiarthroplasty after FNOF. Green = low dose single antibiotic-loaded bone cement, blue = high dose dual antibiotic-loaded bone cement
Study results: Deep SSI reduction from 3.5% to 1.1% in hip hemiarthroplasty after FNOF. Green = low dose single antibiotic-loaded bone cement, blue = high dose dual antibiotic-loaded bone cement

Find out more about the product features of COPAL® G+C bone cement