Carboplatin

Diammine-(1,1-cyclobutanedicarboxylato)platinum(II)

CAS Number: 41575-94-4

Structure Carboplatin

Formula: [Pt(NH3)2(cbdc)]

Monographs: USP, Ph. Eur., JP *

Drug Master File: available on request

* Monographs are available on request

Chemical Properties

Appearance:

  • Form: Solid
  • Color: White

Odor: Odorless

Change in condition

  • Melting point/Melting range: Undetermined.
  • Boiling point/Boiling range: Undetermined.

Flash point: Not applicable.

Flammability (solid, gaseous): Product is not flammable.

Ignition temperature:

Decomposition temperature: >200 °C (>392 °F)

Auto igniting: Product is not selfigniting.

Danger of explosion: Product does not present an explosion hazard.

Vapor pressure: Undetermined.

Density:

  • Bulk density: Not determined.

Solubility in / Miscibility with water at 20 °C (68 °F): 18 g/l

Handling Information

Precautions for safe handling

  • Wear protective equipment. Keep unprotected persons away.
  • Work only in fume cabinet.
  • Store under lock and key and with access restricted to technical experts or their assistants only.
  • Open and handle receptacle with care.

Information about protection against explosions and fires:

  • Keep respiratory protective device available.

Storage Information

Requirements to be met by storerooms and receptacles:

  • Store in a cool location.
  • Store in dry conditions.

Information about storage in one common storage facility:

  • Store away from flammable substances.
  • Store away from foodstuffs.

Further information about storage conditions:

  • Protect from exposure to the light.
  • Keep receptacle tightly sealed.

Risk & Safety Information

Classification of the substance or mixture

  • Muta. 1B H340 May cause genetic defects.
  • Carc. 1A H350 May cause cancer.
  • Repr. 2 H361 Suspected of damaging fertility or the unborn child.
  • Acute Tox. 4 H302 Harmful if swallowed.
  • Skin Irrit. 2 H315 Causes skin irritation.
  • Eye Irrit. 2A H319 Causes serious eye irritation.
  • STOT SE 3 H335 May cause respiratory irritation.

Classification according to Directive 67/548/EEC or Directive 1999/45/EC

  • Toxic
  • May cause cancer. May cause heritable genetic damage.
  • Harmful
  • Harmful if swallowed. Possible risk of harm to the unborn child.
  • Irritant
  • Irritating to eyes, respiratory system and skin.
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